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KMID : 0367419940370020250
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Journal of Korean Pediatric Society
1994 Volume.37 No. 2 p.250 ~ p.256
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Acute Tubular Necrosis Associated with Typhoid Fever
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신필진
이호석/조병수/안창일/양문호
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Abstract
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Acute tubular necrosis has been rarely reported as a complication of typhoid fever in the literature.
We experienced four cases of acute tubular necrosis associated with typhoid fever in children. Patients showed significant titer of widal reaction associated with acute renal failure and one of them rised in 2 months after onset of clinical
symptoms.
Renal biopsy findings were compatible with acute tubular necrosis and immune complexes were not deposited in the glomeruli. Clinical and urinary findings were normalized by hemodialysis and antibiotic therapies.
In conclusion, close longterm follow up of widal titer is mandatory in acute tubular necrosis, especially when associated with high fever.
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